Vitamin-D deficiency as a predisposing cause for COVID- 19 morbidities

The Corona virus disease (COVID-19) mortality is increasing day to day due to the presence of comorbidities and respiratory failure. The knowledge about the protective risk factors in associations with COVID-19 is still an assumption. Vitamin D protects against acute lung injury through enhanced expression Angiotensin-Converting Enzyme-2 and low levels were associated with upper respiratory tract infections. The increase in COVID-19 mortality rates is due to microvascular thrombosis which leads to respiratory failure and death. Previous literature showed that the protective role of Vitamin D on COVID-19 in various countries, but in a country like India the association with Vitamin D deficiency and COVID-19 mortality rate yet to be ruled out. Hence present review aimed to derive the association between COVID-19 mortality and deficiency of Vitamin D in India. The present brief review enlightened the positive association of vitamin-D deficiency with COVID-19 mortality.