The effect of maternal BMI, smoking and alcohol on congenital heart diseases: a Mendelian randomisation study.

K. Taylor,R. E. Wootton,Q. Yang,S. Oddie,J. Wright,T. C. Yang,M. Magnus,O. Andreassen,M. C. Borges,M. Caputo,D. A. Lawlor

BMC medicine（2023）

引用 2|浏览21

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摘要

Our results do not provide robust evidence of an effect of maternal BMI, smoking or alcohol on offspring CHDs. However, results were imprecise. Our findings need to be replicated, and highlight the need for more and larger studies with maternal and offspring genotype and offspring CHD data.

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关键词

ALSPAC, BiB,Congenital heart disease,Mendelian randomisation,MoBa,Risk factors

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