Three-dimensional imaging of a peripilar cast and compound follicle in frontal fibrosing alopecia

Frontal fibrosing alopecia (FFA) has become a frequent diagnosis for dermatologists and dermatopathologists. Even though the disease can be recognized clinically, pathologic confirmation is often necessary, particularly in early disease. We have previously shown that a 2-mm dermatoscopy-guided biopsy is effective in diagnosing the disease, thereby allowing histopathologic confirmation, despite the presence of minimal scarring.1 The aim of this study was to better characterize a single disease focus in FFA, namely the peripilar cast, with a variety of imaging modalities.