Longitudinal Arrhythmic Risk Assessment Based on Ejection Fraction in Patients with Recent-Onset Nonischemic Dilated Cardiomyopathy

•Primary prevention ICD indications in nonischemic DCM are still a matter of debate.•Strategies based on LVEF after 3 months of therapy failed to demonstrate efficacy.•Twenty-four months may be better for evaluation of DCM patients for ICD implantation.•Early reduction of LV diameter on therapy identifies patients improving LVEF to >35%.•Such late improvement is associated with lower long-term arrhythmic risk.