IKKα-Mediated Noncanonical NF-κB Signaling Is Required To Support Murine Gammaherpesvirus 68 Latency In Vivo

Brandon Cieniewicz,Varvara Kirillov, Isabel Daher,Xiaofan Li,Darby G. Oldenburg,Qiwen Dong,Julie A. Bettke,Kenneth B. Marcu,Laurie T. Krug

Journal of Virology（2022）

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摘要

The latency programs of the human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) are associated with B cell lymphomas. It is critical to understand the signaling pathways that are used by gammaherpesviruses to establish and maintain latency in primary B cells.

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support murine gammaherpesvirus,signaling

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