Cardiovascular protection effect of a Northeastern Brazilian lyophilized red wine in spontaneously hypertensive rats

Natália T.M. Calzerra,Mayara P. Melo, Pablo F. Santos,Kívia S. Assis,Priscilla M.P. Maciel, Renata L.P. Vieira, Fátima de L.A.A. Azevedo,Angela M.T.M. Cordeiro,Bruno R.L.A. Meireles,Islania G.A. Araújo,Robson C. Veras,Isac A. Medeiros

Journal of Functional Foods（2022）

引用 3|浏览8

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摘要

•Northeastern Brazilian lyophilized red (LRW-RSCS) wine lowers blood pressure in SHR.•LRW-RSCS reduced endothelial dysfunction and improved vascular remodeling in SHR.•In SHR, LRW-RSCS attenuated platelet hyper aggregation and generation of ROS.•The cardioprotective effects of LRW-RSCS in SHR may be linked to a reduction in ROS.

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关键词

Essential hypertension,Brazilian red wine,Endothelial dysfunction,Vascular alterations,Mesenteric resistance arteries,Spontaneously hypertensive rats

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