Electrochemically driven assembly of framework nucleic acids

•The utilization of an electrochemical chip to synthesis DNA nanostructures was firstly developed.•Tetrahedron DNA nanostructures of different sizes (20 bp, 26 bp and 37 bp) and octahedral DNA nanostructure were successfully assembled within 6 min.•The prepared DNA nanostructures exhibit the same structural characteristics and electrochemical performance in comparison to the ones fabricated with thermal annealing method.•The relations between electric potential and pH value were built.