CRISPR/Cas9 mediated disruption of Inositol Pentakisphosphate 2-Kinase 1 (TaIPK1) reduces phytic acid and improves iron and zinc accumulation in wheat grains

•This study, for the first time, used CRISPR/Cas9 to disrupt TaIPK1 gene in wheat.•Disruption of TaIPK1 gene reduces phytic acid and enhanced Iron and Zinc in wheat grains.•This study will help to develop the biofortified wheat and reducing the malnutrition.•This study provided a great resource for the development of biofortified wheat using CRISPR/Cas9.