Application of hiPSC as a Drug Tester Via Mimicking a Personalized Mini Heart

FRONTIERS IN GENETICS(2022)

引用 1|浏览14
暂无评分
摘要
Human induced pluripotent stem cells (hIPSC) have been used to produce almost all types of human cells currently, which makes them into several potential applications with replicated patient-specific genotype. Furthermore, hIPSC derived cardiomyocytes assembled engineering heart tissue can be established to achieve multiple functional evaluations by tissue engineering technology. This short review summarized the current advanced applications based on the hIPSC derived heart tissue in molecular mechanisms elucidating and high throughput drug screening.
更多
查看译文
关键词
IPSC, disease model, tissue engeneering, heart in dish, drug testing
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要