Chronic hypometabolism in striatum and hippocampal network after traumatic brain injury and their relation with memory impairment – [18F]-FDG-PET and MRI 4 months after fluid percussion injury in rat

Amna Yasmin,Kimmo Jokivarsi,Pekka Poutiainen,Asla Pitkänen,Olli Gröhn,Riikka Immonen

Brain Research（2022）

引用 3|浏览9

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摘要

•Striatum has metabolic deficits in chronic stage after lateral fluid percussion injury.•[18F]-FDG-PET shows low glucose uptake across hippocampal network.•Striatal hypometabolism identifies rats with severe memory impairment.•MRI: Atrophy or cerebral blood flow do not correlate with glucose uptake.

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关键词

Brain trauma,Caudate putamen,Cerebral blood flow,Experimental TBI,Glucose uptake,Positron emission tomography

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