Denoisereg: Unsupervised Joint Denoising and Registration of Time-Lapse Live Cell Microscopy Images Using Deep Learning

Image registration is important for analysing time-lapse live cell microscopy images. However, this is challenging due to significant image noise and complex cell movement. We propose a novel end-to-end trainable deep neural network for joint denoising and affine registration of temporal live cell microscopy images. Our network is trained unsupervised, and only a single network is required for bot...