Diagnostic and Therapeutic Implications of Sortilin Expressed on the Surface of Bladder Carcinoma Cells.

Ali-Ahmad Bayat,Niloufar Sadeghi,Ghazaleh Fazli,Mohammad Reza Nowroozi,Solmaz Ohadian Moghadam,Amin Radmanesh, Mohammadjavad Hedayatshodeh,Ali Reza Sarrafzadeh,Omid Zarei,Fatemeh Ghaemimanesh,Hodjattallah Rabbani

Iranian journal of pathology（2022）

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摘要

The overexpression of sortilin in bladder tumor cells and its potential in inducing apoptosis via directed targeting with the specific monoclonal antibody may represent this protein as a potential candidate of targeted therapy in bladder carcinoma.

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关键词

Bladder cancer,Flow cytometry,Monoclonal antibody,Sortilin

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