Effects of prenatal exposure to maternal COVID-19 and perinatal care on neonatal outcome: results from the INTERCOVID Multinational Cohort Study

Francesca Giuliani,Daniel Oros,Robert B Gunier,Sonia Deantoni,Stephen Rauch,Roberto Casale,Ricardo Nieto,Enrico Bertino,Albertina Rego,Camilla Menis,Michael G Gravett,Massimo Candiani,Philippe Deruelle,Perla K García-May,Mohak Mhatre,Mustapha Ado Usman,Sherief Abd-Elsalam,Saturday Etuk,Raffaele Napolitano,Becky Liu,Federico Prefumo,Valeria Savasi,Marynéa Silva Do Vale,Eric Baafi,Shabina Ariff,Nerea Maiz,Muhammad Baffah Aminu,Jorge Arturo Cardona-Perez,Rachel Craik,Gabriela Tavchioska,Babagana Bako,Caroline Benski,Fatimah Hassan-Hanga,Mónica Savorani,Loïc Sentilhes,Maria Carola Capelli,Ken Takahashi,Carmen Vecchiarelli,Satoru Ikenoue,Ramachandran Thiruvengadam,Constanza P Soto Conti,Irene Cetin,Vincent Bizor Nachinab,Ernawati Ernawati,Eduardo A Duro,Alexey Kholin,Jagjit Singh Teji,Sarah Rae Easter,Laurent J Salomon,Adejumoke Idowu Ayede,Rosa Maria Cerbo,Josephine Agyeman-Duah,Paola Roggero,Brenda Eskenazi,Ana Langer,Zulfiqar A Bhutta,Stephen H Kennedy,Aris T Papageorghiou,Jose Villar

American Journal of Obstetrics and Gynecology（2022）

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摘要

In this multinational cohort study, COVID-19 in pregnancy was associated with increased maternal and neonatal complications. Cesarean delivery was significantly associated with newborn COVID-19 diagnosis. Vaginal delivery should be considered the safest mode of delivery if obstetrical and health conditions allow it. Mother-to-child skin-to-skin contact, rooming-in, and direct breastfeeding were not risk factors for newborn COVID-19 diagnosis, thus well-established best practices can be continued among women with COVID-19 diagnosis.

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birthweight,breastfeeding,cesarean delivery,cohort,COVID-19,feeding problems,hospital stay,infections,intrauterine growth restriction,morbidity,mortality,multicenter study,neonatal intensive care unit admission,neonatal outcomes,neonate,neurologic outcome,newborn,perinatal practices,preeclampsia,pregnancy,preterm birth,respiratory support,respiratory symptoms,risk ratio,rooming-in,SARS-CoV-2,SARS-CoV-2 exposure,skin-to-skin,small for gestational age

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