Task engagement turns on spatial maps

NATURE NEUROSCIENCE(2022)

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摘要
Pettit, Yuan and Harvey find that hippocampal spatial maps degrade when mice voluntarily disengage from a navigation task, even without changes in sensory or self-motion cues. This finding suggests that internal state could have an active role in supporting navigational coding and, perhaps, spatial memory.
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关键词
Multiphoton microscopy,Navigation,Neural circuits,Biomedicine,general,Neurosciences,Behavioral Sciences,Biological Techniques,Neurobiology,Animal Genetics and Genomics
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