Lonicera caerulea ( Haskap berries): a review of development traceability, functional value, product development status, future opportunities, and challenges.

is a honeysuckle plant with a long development history. It is defined as a "homology of medicine and food" fruit because it is rich in bioactive substances. By-products (such as pomace, leaves, stems, and flowers), which also have beneficial values, will be produced during processing. Nevertheless, the reuse of derivatives and the further development of new products of are still a challenge. Firstly, this paper traced the development history of and summarized its primary nutrients and bioactive substances, subsequently discussed the research progress and underlying molecular mechanisms of its functional properties, and introduced the application and potential of in the fields of food, health products, cosmetics, medicine, and materials. Finally, this paper put forward the future research direction to promote the development of the industry. To sum up, , as a potential raw material, can be used to produce more functional products. Besides, more in-depth clinical trials are needed to clarify the specific molecular mechanism of the practical components of and improve the rate of development and utilization.HighlightsThe original species of subgroup had appeared on the earth as early as the end of the third century. has been introduced into North America since the 18th century, but the introduction process has not ended until now. widely exists in Eurasia and North America and it has excellent cold tolerance, early maturity and ornamental.The fruits, stems, leaves and flowers of all have bioactive value, but the specific molecular mechanism and utilization need to be improved. has been widely used in food, medicine, health products, cosmetics and materials, but there are still great challenges.