COVID-19 in vaccinated versus unvaccinated hematologic malignancy patients.

Catherine DeVoe,Shraddha Pandey,Dayana Shariff,Shagun Arora,Timothy J Henrich,Deborah S Yokoe,Charles R Langelier,Venice Servellita,Charles Chiu,Steve Miller,Jennifer M Babik,Peter Chin-Hong,Monica Fung

Transplant infectious disease : an official journal of the Transplantation Society（2022）

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摘要

The effect of vaccination on severity of subsequent COVID-19 in patients with hematologic malignancies (HMs) is unknown. In this single-center retrospective cohort study, we found no difference in severity of COVID-19 disease in vaccinated (n = 16) versus unvaccinated (n = 54) HM patients using an adjusted multiple logistic regression model. Recent anti-B-cell therapy was associated with more severe illness.

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关键词

COVID-19,breakthrough infection,hematologic malignancy

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