Inhibiting the aberrant PACT-p53 axis activation ameliorates spinal cord ischaemia–reperfusion injury in rats

Yan Dong,Xuan Jiang,Fengshou Chen,Dan Wang,Zaili Zhang

International Immunopharmacology（2022）

引用 1|浏览4

暂无评分

摘要

•The expression of PACT is substantially upregulated after SCII.•Silencing PACT inhibits the aberrant PACT-p53 axis activation after SCII.•Silencing PACT protected against SCII by inhibiting neuroapoptosis and inflammation.

查看译文

关键词

Spinal cord ischaemia–reperfusion injury,PACT,p53,Neuroapoptosis,Neuroinflammation

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要