Identification of Alternative Splicing and LncRNA Genes in Brain Tissues of Fetal Mice at Different Developmental Stages.

Combinatorial chemistry & high throughput screening(2023)

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摘要
Our results preliminarily illustrated the differentially expressed lncRNAs and mRNAs, both of which were derived from the same parent genes, during brain development in fetal mice, which suggests that alternative splicing of lncRNA exists during brain development. Besides, our study provides a perspective on critical genes for brain development, which might be the underlying therapeutic targets for developmental brain diseases in children.
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关键词
Brain development,alternative splicing,fetal mice,high-throughput sequencing,long non-coding RNAs,mRNAs
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