Pro-inflammatory immune profile mediated by TNF and IFN-γ and regulated by IL-10 is associated to IgG anti-SARS-CoV-2 in asymptomatic blood donors

Daniel Gonçalves Chaves,Leonardo Camilo de Oliveira,Maria Clara Fernandes da Silva Malta, Isabelle Rocha de Oliveira,Edel Figueiredo Barbosa-Stancioli,Mauro Martins Teixeira,Marina Lobato Martins

Cytokine（2022）

引用 3|浏览2

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摘要

•Older individuals have significantly higher indexes of IgG anti-SARS-CoV-2.•Higher serum levels of IL-10, TNF and IFN- g are associated with IgG anti-SARS-CoV-2.•Higher levels of chemokines in asymptomatic individuals with IgG anti-SARS-CoV-2.•Levels of CCL5, CXCL9 and CXCL10 associated to IgG neutralization of SARS-CoV-2.

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关键词

SARS-CoV-2,COVID-19,Blood donor,Chemokine,Cytokine,Neutralization

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