c-Maf: The magic wand that turns on LSEC fate
Cell Stem Cell（2022）
摘要
In this issue of Cell Stem Cell, Gomez-Salinero et al. (2022) identify c-Maf as a driver for murine liver sinusoidal endothelial cell (LSEC) fate and function during liver development, homeostasis, and repair. Similarly, c-Maf defines human LSECs, and its overexpression specializes generic HUVECs into functional induced-LSECs, potentiating regenerative therapeutics.
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