Patients With Inflammatory Bowel Diseases Have Impaired Antibody Production After Anti-SARS-CoV-2 Vaccination: Results From a Panhellenic Registry.

Eirini Zacharopoulou,Eleni Orfanoudaki,Maria Tzouvala,George Tribonias,Georgios Kokkotis,Vassiliki Kitsou, Foteini Almpani, Aggeliki Christidou,Nikolaos Viazis,Gerassimos J Mantzaris,Maria Tsafaridou,Konstantinos Karmiris,Angeliki Theodoropoulou,Evgenia Papathanasiou,Evanthia Zampeli,Spyridon Michopoulos,Stefanos Tigkas,Georgios Michalopoulos,Efrossini Laoudi,Pantelis Karatzas,Iordanis Mylonas,Nikolaos Kyriakos,Christos Liatsos, Theodora Kafetzi,Georgios Theocharis, Styliani Taka, Konstantina Panagiotopoulou,Ioannis E Koutroubakis,Giorgos Bamias

Inflammatory bowel diseases（2023）

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摘要

Patients with IBD have impaired antibody responses to anti-SARS-CoV-2 vaccination, particularly those receiving viral vector vaccines and those on anti-TNFα treatment. Older age also hampers antibody production after vaccination. For those low-response groups, administration of accelerated or prioritized booster vaccination may be considered.

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关键词

COVID-19 vaccines,Crohn’s disease,IBD,antibody response,ulcerative colitis

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