Bone marrow-derived inducible microglia-like cells ameliorate motor function and survival in a mouse model of amyotrophic lateral sclerosis

Shuhei Kobashi,Tomoya Terashima,Miwako Katagi,Makoto Urushitani,Hideto Kojima

Cytotherapy（2022）

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摘要

Intraspinal transplantation of BM-iMG cells demonstrated therapeutic effects in a mouse model of ALS. Further studies and clinical applications in patients with ALS are expected in the future.

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关键词

amyotrophic lateral sclerosis,BM-iMG cells,bone marrow-derived cells,GM-CSF,IL-4,neuroprotective microglia

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