Analysis of cell-free fetal DNA in 16,843 pregnant women from a single center in China using targeted sequencing approach

Yang Zhou, Yinfeng Wang,Frank Peprah Addai,Xiaofeng Li,Xiuwen Zhang,Haitao Liu,Gongda Yang, Fengbo Zeng,Tingya Jiang,Junling Liu

Placenta（2022）

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摘要

•cffDNA could be detected on the 4th week of gestation.•cffDNA had 3 inflection points at the 10th, 19th and 30th week of gestation.•cffDNA has met the NIPT requirements after 9 weeks gestational age.

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关键词

Cell-free fetal DNA,Gestational age,Non-invasive prenatal testing,SNP-based targeted deep sequencing

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