How to handle a delayed or missed dose of edoxaban in patients with non-valvular atrial fibrillation? A model-informed remedial strategy.
British journal of clinical pharmacology（2022）
摘要
PK/PD modelling and simulation are effective in developing and evaluating the remedial strategies of edoxaban, which can help maximise its therapeutic effect.
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关键词
adherence,anticoagulants,edoxaban,modelling and simulation,pharmacokinetic-pharmacodynamic
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