Decreasing Tryptophan and Increasing Neopterin Plasma Levels During Pregnancy are Associated with High First Trimester Porphyromonas gingivalis K-Serotype IgG Serointensity in a Cohort of Hispanic Women.

Teodor T Postolache,Sanjaya K Upadhyaya,Anna M Spector,Iqra Mohyuddin,Niel Constantine,Robert K Ernst,Abhishek Wadhawan,Samia Valeria Ozorio Dutra,Aline Dagdag,Hina Makkar,Christopher A Lowry,Faisal Akram,Dietmar Fuchs,Lisa A Brenner,Maureen W Groer,Mark A Reynolds

Current topics in medicinal chemistry（2022）

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摘要

If replicated in larger studies and further characterized clinically, radiologically, and microbiologically, our results may potentially lead to novel interventional targets, as well as the development of more complete prognostic and predictive interactive biomarkers for adverse obstetrical outcomes and peripartum depression, and their prevention.

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关键词

Hispanic.,IgG Serointensity,Kynurenine,Kynurenine pathway,Neopterin,Porphyromonas gingivalis,Porphyromonas gingivalis K-Serotype,Pregnancy,Tryptophan

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