Mechanisms underlying the therapeutic effects of Qingfeiyin in treating acute lung injury based on GEO datasets, network pharmacology and molecular docking

•Qingfeiyin (QFY),a traditional Chinese herbal decoction, has shown significant clinical efficacy against acute lung injury (ALI).•We found that QFY works through the PI3K-Akt and MAPK signaling pathways in ALI treatment.•QFY interacts with targets related to inflammation, apoptosis, and oxidative stress.•The present study made a comprehensive analysis to elucidate the active ingredients and the mechanisms of action of QFY by a bioinformatics approach for the first time.