Metabolomics profiling of human exhaled breath condensate by SPME/GC × GC-ToFMS: Exploratory study on the use of face masks at the level of lipid peroxidation volatile markers

•HS-SPME/GC × GC–ToFMS development for EBC metabolome profiling.•Extraction of EBC, using DVB/CAR/PDMS coating (40.0 ± 0.1 °C and physiological pH)•Most detailed study on the endogenous and exogenous EBC volatile metabolites.•EBC metabolites were determined at pg level.•The use of surgical facemasks not significantly affect the levels of lipid peroxidation markers, neither SpO2.