G-CSF: A vehicle for communication between trophoblasts and macrophages which may cause problems in recurrent spontaneous abortion

Peng Gao,Ying Zha,Lijie Wei,Xuan Zhou,Shenglan Zhu,Huiting Zhang,Xuan Gao,Yi Jiang,Yuting Chen,Jiaqi Li,Jingyi Zhang,Jun Yu,Shaoshuai Wang,Haiyi Liu,Ling Feng

Placenta（2022）

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摘要

•G-CSF is decreased in patients with RSA comparing with normal pregnant women.•G-CSF regulates trophoblast - macrophage communication through exosomes.•G-CSF decreases the rate of abortion in RSA mice.

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关键词

Recurrent spontaneous abortion,Trophoblast,Macrophage,G-CSF,Exosome

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