Functionality of natural killer cells in obese asthma phenotypes.

Leyla Pur Ozyigit,Esin Cetin Aktas,Yusuf Metin Gelmez,Ayse Bilge Ozturk,Bilun Gemicioglu,Gunnur Deniz

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology（2022）

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摘要

Our study suggests an impaired NK receptor expression, activation and reduced cytotoxicity in OA patients together with variances between different subtypes of this phenotype. This data would be beneficial for tailoring a more personalized treatment strategy combatting steroid resistance and frequent exacerbations in this group of patients.

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关键词

CD107a,CD69,NK,allergy,asthma,cytotoxicity,early-onset,obesity,phenotype

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