Results and insights from a phase I clinical trial of Lomecel-B for Alzheimer's disease.

Mark Brody,Marc Agronin, Brad J Herskowitz,Susan Y Bookheimer,Gary W Small, Benjamin Hitchinson,Kevin Ramdas,Tyler Wishard, Katalina Fernández McInerney,Bruno Vellas,Felipe Sierra,Zhijie Jiang,Lisa Mcclain-Moss,Carmen Perez,Ana Fuquay,Savannah Rodriguez,Joshua M Hare,Anthony A Oliva,Bernard Baumel

Alzheimer's & dementia : the journal of the Alzheimer's Association（2023）

引用 17|浏览26

暂无评分

摘要

Our results support the safety of Lomecel-B for AD, suggest clinical potential, and provide mechanistic insights. This early-stage study provides important exploratory information for larger efficacy-powered clinical trials.

查看译文

关键词

Alzheimer disease,Lomecel-B,anti-inflammatory agents,biological therapy,bone marrow mesenchymal stem cell,clinical trial,cytokines,hippocampus,human bone marrow,inflammation,inflammation mediators,interleukins,medicinal signaling cell,mesenchymal stem cell,mesenchymal stromal cell,multipotent stem cells,neuroimaging,neuroinflammatory diseases,randomized controlled trial,regenerative medicine,vascular,vascular endothelial cell growth factor

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要