Longitudinal assessment of aggression and circadian rhythms in the APPswe mouse model of Alzheimer`s disease

•Alzheimer's disease patients show agitation/aggression and circadian rhythm disorder.•APPswe mice present higher aggression at an early age only.•APPswe mice present raised locomotor activity relative to controls until later ages.•APPswe mice could be used at specific ages to model a subset of agitation-relevant behaviors.