Metabolic footprint in young, middle-aged and elderly rats with melatonin deficit

Jana Tchekalarova,Petar Hrischev,Petya Ivanova,Nikolai Boyadjiev,Katerina Georgieva

Physiology & Behavior（2022）

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摘要

•Pinealectomy in rats represents a relevant model for the evaluation of aging.•It impairs physiological, metabolic, and biochemical markers in young adult rats.•Melatonin deficit doesn't affect aging markers in older rats.

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关键词

Pinealectomy,Aging,Metabolic and physiological parameters,Rat

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