Circulating Biomarkers Predict Symptomatic but Not Asymptomatic Carotid Artery Stenosis.

Shahab Fatemi,Stefan Acosta,Moncef Zarrouk,Gunnar Engström,Olle Melander,Anders Gottsäter

Cerebrovascular diseases (Basel, Switzerland)（2022）

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摘要

Plasma biomarkers NT pro-BNP, MR-proADM, cystatin C, and CRP were independently associated with incident symptomatic CAS, whereas no such association could be demonstrated with incident asymptomatic CAS. As these biomarkers indicate future development of clinically relevant atherosclerotic CAS, their potential utility in relation to intensified preventive measures and selection of potential candidates for carotid surgery should be further evaluated.

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关键词

Asymptomatic,Biomarkers,C-reactive protein,Carotid artery stenosis,Copeptin,Cystatin C,Lipoprotein-associated phospholipase A2,Midregional proadrenomedullin,Midregional proatrial natriuretic peptide,N-terminal pro-brain natriuretic peptide,Proneurotensin,Symptomatic

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