Performance of the Sofia SARS-CoV-2 rapid antigen test as frontline test in a university hospital, Germany

Diagnostic Microbiology and Infectious Disease(2022)

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摘要
•We evaluated the performance of the Sofia SARS-CoV-2 rapid antigen test (Ag-RDT)•A total of 7877 patients were included in a prospective and monocentric study•Overall sensitivity of Ag-RDT compared to RT-PCR was 62.9% and specificity 99.4%•In a subset of symptomatic and RT-PCR positive patients sensitivity was 72.1%•The Ag-RDT proved to be a rapid tool to detect patients with high viral loads (Ct-value ≤25)
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关键词
SARS-CoV-2,Rapid antigen testing,RT-PCR,Clinical performance,Real-world data
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