Interaction between TMEFF1 and AHNAK proteins in ovarian cancer cells: Implications for clinical prognosis

Xin Nie,Mingjun Zheng,Lingling Gao,Yuexin Hu,Yuan Zhuang,Xiao Li,Liancheng Zhu,Juanjuan Liu,Bei Lin

International Immunopharmacology（2022）

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摘要

•The protein–protein interaction (PPI) between TMEFF1 and ANHAK was confirmed for the first time.•AHNAK is an independent risk factor for the prognosis of ovarian cancer.•TMEFF1 regulates the expression of ANHAK.•AHNAK activates MAPK signal pathways.

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关键词

TMEFF1,AHNAK,Ovarian cancer,MAPK,Protein interact

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