Noninvasive estimation of aortic pressure waveform based on simplified Kalman filter and dual peripheral artery pressure waveforms

•The article proposes a novel SKF approach for reconstructing the central aortic pressure waveform from dual peripheral artery pressure waveforms.•The main aim is to establish a cross-relation with the peripheral pressure measured noninvasively, and to use SKF's iterative optimization approach to derive an adaptive transfer function.•The adaptive transfer function provides a patient-specific method to meeting the demand for a clinically useful way to reliably estimate central aortic pressure from non-invasive peripheral pressure measurements.•The performance of the proposed method is superior to that of other state-of-the-art methods.