Effects of SVEP1 on Lung Squamous Cell Carcinoma and its Association with Tumor Mutation Burden, Prognosis, and Immune Regulation.

Yu Luo,Min Zhang,Zhibo Wang,Zhihua Li,Xiru Chen,Juan Cao,Jun Que,Liang Chen,Xiaheng Deng

Combinatorial chemistry & high throughput screening（2023）

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摘要

SVEP1 mutation and its mRNA expression are related to tumor mutation burden and cancer immunity in lung squamous cell carcinoma. Our findings reveal the underlying mechanisms, indicating that SVEP1 may be a prognostic marker of lung squamous cell carcinoma.

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关键词

SVEP1,lung squamous cell carcinoma,microsatellite instability,prognosis,tumor immune infiltration,tumor mutation burden

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