Altered regional homogeneity and cognitive impairments in first-episode schizophrenia: A resting-state fMRI study

Asian Journal of Psychiatry(2022)

引用 8|浏览18
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摘要
•Patients with schizophrenia displayed severe and widespread cognitive deficits measured by MCCB.•The abnormal ReHo were distributed in SFG, ACC, PCC, cuneus and occipital lobe in schizophrenia.•ACC and PCC were correlated with PANSS scores.•Brain regions with decreased ReHo were associated with cognitive domains.•There may be compensatory neural activity in ACC.
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关键词
First-episode schizophrenia,Functional magnetic resonance imaging,Regional homogeneity,Cognition deficits,MCCB
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