Hsa_circ_0087352 promotes the inflammatory response of macrophages in abdominal aortic aneurysm by adsorbing hsa-miR-149-5p

International Immunopharmacology(2022)

引用 13|浏览7
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摘要
•Hsa_circ_0087352 is up-regulated in human abdominal aortic aneurysms.•Hsa_circ_0087352 regulates LPS-induced macrophage activation via sponging endogenous hsa-miR-149-5p.•Hsa_circ_0087352 regulates human vascular smooth muscle cell apoptosis via proapoptotic cytokines.
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关键词
Abdominal aortic aneurysm,Circular RNA,Macrophage,Inflammation,ERK/NF-κB
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