Infection and pathogenesis of the Delta variant of SARS-CoV-2 in Rhesus macaque.

Ge Gao,Xue Hu,Yiwu Zhou,Juhong Rao,Xiaoyu Zhang,Yun Peng,Jiaxuan Zhao,Yanfeng Yao,Kunpeng Liu,Mengying Liang,Hang Liu,Fei Deng,Han Xia,Chao Shan,Zhiming Yuan

Virologica Sinica（2022）

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摘要

•Delta variant of SARS-CoV-2 can effectively infect the Rhesus macaque.•Delta variant grows faster than the early strain isolated from Wuhan in late 2019.•Shedding pattern, viral load and disease severity of Delta variant are similar to the early strain isolated from Wuhan.•This study supports the attributed rapid disease spread of the Delta variant.

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