Emergence of SARS-CoV-2 Alpha lineage and its correlation with quantitative wastewater-based epidemiology data

Elena Radu,Amandine Masseron,Fabian Amman,Anna Schedl,Benedikt Agerer,Lukas Endler,Thomas Penz,Christoph Bock,Andreas Bergthaler,Julia Vierheilig,Peter Hufnagl,Irina Korschineck,Jörg Krampe,Norbert Kreuzinger

Water Research（2022）

引用 13|浏览22

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摘要

•Alpha lineage spotted in Vienna wastewater 1 month before the first clinical case.•WBE proved to be a powerful tool to early detect and monitor circulating lineages.•SARS-CoV-2 signature mutations play a key role in shedding concentrations.•Different shedding behavior was noticed in wastewater due to Alpha variant.

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关键词

SARS-CoV-2 dynamics,WBE (Wastewater Based Epidemiology),Alpha lineage,Signature mutations,epidemiological data,whole genome sequencing

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