Association of sports activity during the first five years of survival with quality of life among Chinese breast cancer survivors

Abstract Background: The objective of this study was to investigate the association between participation of sports activity (SA) and quality of life (QoL) among Chinese women with early stage breast cancer (BC) during the first five years post BC diagnosis. Methods: BC survivors underwent assessment of QoL and level of SA at 3 time-points: 18-, 36- and 60-months after diagnosis. SA was measured using a validated modified Chinese Baecke questionnaire in the prior 12 months; QoL was measured using EORTC-QLQC30. Results: In total, 1289, 1125 and 1116 BC survivors were included at 18-, 36- and 60-month follow-up, respectively. At 18-month, the percentages of patients belonged to no [0 metabolic equivalent of task (MET)-hours per week], low-level (<10 MET-hours/week) and high-level (≥10 MET-hours/week) SA groups were 20.7%, 45.5% and 33.8%, respectively; the corresponding figures at 36-month were 29.4%, 38.9% and 31.6%, respectively; and tat of 60-month were 32.8%, 36.7% and 30.5%, respectively. Generalized Estimating Equations analyses showed that higher level of SA was associated with better QoL in several items, including global health status/QoL, physical functioning, role functioning and emotional functioning (P for trend < 0.05 for all), as well as less symptoms in fatigue, pain, loss of appetite and constipation (P for trend < 0.05 for all). Conclusions: Findings from the present study support the notion that SA has beneficial effect on QoL during the first 5 years of BC survivorship. Health promotion programs should encourage participation for SA after breast cancer diagnosis.Acknowledgements: This work was supported by World Cancer Research Fund International (Grant Number WCRF 2010/249 and WCRF 2014/1197) and Madam Diana Hon Fun Kong Donation for Cancer Research. Citation Format: Winnie Yeo, Yuanyuan Lei, Kali Cheung, Roselle Lee, Carol Kwok, Ashely Cheng, Ashely Cheng, Frankie Mo, Suzanne Ho. Association of sports activity during the first five years of survival with quality of life among Chinese breast cancer survivors [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P4-11-10.