Peptide Antibiotics Produced by Bacillus Species: First Line of Attack in the Biocontrol of Plant Diseases

Bacillus spp. contain a wide arsenal of weapons against plant pathogens such as bacteria, fungi, and oomycetes, including antibiotic peptides as part of the first line of attack and plant protection. In general, such peptides, based on their biosynthetic pathways, can be of ribosomal or non-ribosomal origin. In both cases, a complex genetic structure is required that codes for different enzyme complexes. Here, we review the capabilities and advantages of Bacillus species to antagonize and control diseases of different crops through the production of peptide antibiotics. Finally, this chapter discusses the potential of engineered microbes and different types and mechanisms of action of non-ribosomally or ribosomally synthesized peptide antibiotics in Bacillus spp., with the final goal of reducing the use of toxic chemicals in agriculture.