Quality control of Zingiberis Rhizoma and its processed products by UHPLC-Q-TOF/MS-based non-targeted metabonomics combining with SIBDV method

•A novel non-targeted metabonomics method was applyed in discrimination of ZR, ZRP and CG.•A comprehensive SIBDV method was firstly proposed to characterize and screening gingerols in ZR, ZRP and CG.•A total of 59 gingerols were identified, which was the first comprehensive and systematic presentation of gingerols.•PCA and OPLS-DA showed differences, and 33 differential components were characterized as potentially chemical markers.•These findings provides promising perspectives in the quality control of ZR, ZRP and CG.