Cu²⁺-Induced self-assembly and amyloid formation of a cyclic d,l-α-peptide: structure and function

Daniel Klose,Sahithya Phani Babu Vemulapalli,Michal Richman,Safra Rudnick,Vered Aisha,Meital Abayev,Marina Chemerovski,Meital Shviro,David Zitoun,Katharina Majer,Nino Wili,Gil Goobes,Christian Griesinger,Gunnar Jeschke,Shai Rahimipour

Physical Chemistry Chemical Physics（2022）

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摘要

The self-assembly of the cyclic d,l-α-peptide generates amyloid-like structures and this process can be arrested at the level of the dimer giving insights into early-stage aggregation and polymorphism.

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Cu2+-Induced self-assembly and amyloid formation of a cyclic d,l-α-peptide: structure and function

Cu²⁺-Induced self-assembly and amyloid formation of a cyclic d,l-α-peptide: structure and function