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The German care high registry for familial hypercholesterolemia –Sex differences, treatment strategies, and target value attainment

F. Fath,W. März,N. Schmidt,I. An Haak,A. Dressel,T. Grammer,M. Kleber,A. Bäßler,F.U. Beil,I. Gouni-Berthold,U. Julius,U. Kassner,J.L. Katzmann,G. Klose,C. König,W. Koenig,A.-C. Koschker,U. Laufs,M. Merkel,B. Otte

SSRN Electronic Journal（2023）

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摘要
•FH is undertreated in Germany compared to guideline recommendations.•Male gender, genetic proof of FH, treatment by a specialist, and ASCVD are associated with increased treatment intensity.•Achieving the LDL-C goals of the latest dyslipidemia guidelines remains challenging if pre-treatment LDL-C is very high.
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关键词
Familial hypercholesterolemia, Cascade screening, Patient registry, Cardiovascular risk, Treatment, Adherence, Low-density lipoproteins
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