Subclinical giant cell arteritis in new onset polymyalgia rheumatica A systematic review and meta-analysis of individual patient data

Andrea K. Hemmig, Daniele Gozzoli, Laura Werlen, Hannah Ewald,Markus Aschwanden, Daniel Blockmans,Elisabeth Brouwer,Russell R.C. Buchanan,Dario Camellino, Corrado Campochiaro,Marco A. Cimmino,Hector Corominas, Viktoria Gloy,Liesbet Henckaerts, Diego Kyburz, Patricia Moya-Alvarado,Claire E. Owen,Mihaela Stegert, Alessandro Tomelleri,Yannick van Sleen

Seminars in Arthritis and Rheumatism（2022）

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摘要

•More than a quarter of patients with PMR may have subclinical GCA at diagnosis.•Meta-analysis of a large patients’ data set could not identify a marker for subclinical GCA.•Classical inflammatory parameters such as ESR and CRP were not associated with subclinical GCA.•A paradigm shift in the assessment of PMR patients in favour of implementing imaging studies should be discussed.

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关键词

Polymyalgia rheumatica,Giant cell arteritis,Subclinical vasculitis,Systematic review,Meta-analysis

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