The 7-Hydroxyflavone attenuates chemotherapy-induced neuropathic pain by targeting inflammatory pathway

Rahim Ullah,Gowhar Ali, Abdur Rasheed,Fazal Subhan,Ajmal Khan,Sobia Ahsan Halim,Ahmed Al-Harrasi

International Immunopharmacology（2022）

引用 11|浏览8

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摘要

•The 7-Hydroxyflavone attenuates peripheral and central nociceptive pain.•The 7-Hydroxyflavone ameliorates carrageenan induced paw edema.•The 7-Hydroxyflavone reduces chemotherapy induced neuropathic pain.•The 7-Hydroxyflavone reduces neuroinflammation and oxidative stress.

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关键词

Paclitaxel,Vincristine,Cytokines,Neuropathic pain,7-Hydroxyflavone,NF-κB,COX-2,5-LOX

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