The visual cortical responses to sinusoidal transcorneal electrical stimulation

•It is the first time to investigate the responses arising in visual cortex to sinusoidal retinal electrostimulation, and to compare the different cortical responses elicited by sinusoidal and rectangular waveforms in vivo.•The optimal stimulation frequency for sinusoidal retinal electrostimulation was approximately 20 Hz.•Sinusoidal retinal electrostimulation is a more efficient strategy than rectangular stimulation in regard to cortical response, especially at low frequency.