Association between KLF6 rs3750861 polymorphism and plasma ceramide concentrations in post-menopausal women with type 2 diabetes

Nutrition, Metabolism and Cardiovascular Diseases(2022)

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摘要
•A relationship between KLF6 rs3750861 genetic variant and plasma ceramide levels is unknown.•In T2DM patients, C/T or T/T genotypes of rs3750861 were associated with higher plasma levels of specific ceramides.•These findings remained significant after adjustment for confounders, including use of lipid-lowering agents.
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Ceramides,KLF6,Type 2 diabetes,T2DM,rs3750861
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